The Saint Louis University Institute for Drug and Biotherapeutic创新 (博彩网址大全-IDBI) is a multidisciplinary association of researchers with a shared interest in drug and biotherapeutic discovery 和发展 to address unmet patient needs. 我们邀请 all University associated faculty with an interest in therapeutic discovery, development, 翻译成 加入IDBI.
博彩网址大全-IDBI brings together experts from a variety of disciplines to share expertise, 激发创意，促进合作. 来自博彩网址大全-IDBI的五位研究人员讨论 this new initiative, as well as their own research and its impact on quality of care 世界各地.
IDBI任务
The IDBI leverages its members’ deep expertise in medicine, biology, engineering, computational and applied chemistry to discover, develop and translate new medical therapies to address unmet patient needs as part of the University’s mission to serve 人类. Further, the IDBI promotes the translation of University research through 以下途径的药物发现和临床前开发:
- Bringing together 博彩网址大全 researchers to share expertise and stimulate ideas in drug discovery 和发展
- Facilitating intra- and inter-institutional translational collaborations
- Facilitating external sponsorship of promising translational research
- Educating members and students on drug discovery 和发展 and creating opportunities 让博彩网址大全学生参与药物开发
- Providing drug discovery consultations and tools to advance translational projects
- 为有前途的药物发现研究提供种子基金
As an academic-based drug discovery institute, the IDBI has as an integral part of 它的使命是教育学生在他们的职业生涯的各个阶段. IDBI成员 teach classes, mentor students, welcome both graduate and undergraduate students into their labs, expanding classroom education into real-world research experience. IDBI成员 create opportunities for 博彩网址大全 undergraduate and graduate students to participate in drug development, including projects in chemistry, biology, pharmacology, computational 商业发展.
The IDBI, in conjunction with 博彩网址大全 Career Services, welcomes the opportunity to discuss with potential partners the recruitment of 博彩网址大全 students into internships, co-ops and 全职工作.
目前的研究和专业知识
博彩网址大全-IDBI is one of the university’s largest institutes, with more than 100 highly 成就和全国知名的成员. 总的来说，这些专家成员 launched several startups and companies, obtained numerous patents and secured more 超过3700万美元的药物研发经费. 目前的研究突出了这一发现 和发展 of therapies for diseases including cancer; chronic pain; central nervous system disorders; liver disease; infectious diseases such as hepatitis B, tuberculosis, fungal infections; genetic disorders including muscular dystrophy and lysosomal storage disease; and neglected diseases.
IDBI成员 advance research encompassing a breadth of human and animal therapeutics with modalities such as small molecules, protein drugs, cell-based treatments, 基因治疗. IDBI成员 also perform research in enabling technologies such as medicinal chemistry, pharmacology, animal models, therapeutic delivery technologies, 结构生物学和计算生物学. 许多IDBI研究人员有一个特殊的 emphasis on diseases of outsize burden on underserved populations, rare diseases, 孤儿或被忽视的疾病.
合作伙伴关系
The IDBI is interested in developing new partnerships with both industry and academia 分享专业知识，激发创意，推动发现. 研究所也欢迎 有兴趣进入我们的核心设施的咨询. 目前,博彩网址大全-IDBI researchers are working with companies ranging from global biotech to specialized early-stage startups on both early- and advanced-stage therapeutic research. 感兴趣 parties can contact Jaffre Athman, director of business development, jaffre.athman@backpaintreatmentcostamesa.com.
IDBI成员 have in-depth experience and expertise in their fields, providing the full range of skills needed for premier drug discovery 和发展. 专业知识 includes target identification and validation, primary drug screening, medicinal chemistry 优化 of screening hits, pharmacological characterization, lead 优化, 以及新疗法的临床试验. IDBI操作物理服务核心 为了提供获得关键药物开发步骤的途径，e.g.，测定发展，化合物 screening/counter screening, target validation, ADME/PK, medicinal chemistry drug 优化. The 博彩网址大全 research community also offers ready access to world class vivarium facilities, world leading vaccine and therapeutic clinical trial capabilities.
合作
Within 博彩网址大全, the IDBI has over 15 collaborative projects ongoing between members of the IDBI that include primary drug screening and discovery with iterative medicinal 化学，体外PK/ADME研究，动物模型.
Outside of 博彩网址大全, members of the IDBI are working with companies and other academic 世界各地的实验室. 项目的复杂性和长度不等，包括化验 development and/or validation, in silico and physical screening, efficacy testing 体外和体内模型，以及admek检测. 与业界合作 sponsored projects have in some cases included long-term support for basic biology, target identification and novel therapy development, as well as sponsoring development of 博彩网址大全 hits and leads, to fixed-duration visiting scientist exchanges, scientific 培训和研究生资助.
博彩网址大全-IDBI资源
资源 are available to members of 博彩网址大全 IDBI and other members of the campus community 点击下面的链接. 这些资源包括关于IDBI创新种子的信息 Grant, the ADME/PK Service, assays available within member labs, access to the IDBI共享驱动器. 查看博彩网址大全-IDBI资源
The IDBI sends to 我们的成员 a bi-weekly newsletter, the IDBI Elixir, with funding announcements, research and educational webinars, news items from the IDBI and 我们的成员. 在这里注册领取药剂.